Animal Tissue Culture
Vittal Mallya Scientific Research Foundation has taken lead in use of natural plant products in control of obesity, diabetes, cholesterol levels and a step further in developing anticancer and anti-inflammatory leads. Several lead molecules developed in house are evaluated for cytotoxic potential and further downstream events. The compounds are screened in different cancer cell lines for various cell based assays. VMSRF has a pilot scale facility for animal tissue culture to study mechanisms explaining the effectiveness of these compounds. Potential target genes regulating cell survival and proliferation implicated in disease development are determined using different molecular techniques. Following in vitro studies in cell lines the lead molecules are further evaluated in vivo.